Spatio-temporal dynamics of rodent-borne diseases STRODE

  • Supervisor: Simon Dellicour, Marius Gilbert
  • Research center: Spatial Epidemiology Lab
  • Research start date: 15.11.2021


There is a general link between environment, seed production, and rodent-borne disease outbreaks, but how do those links vary for diseases with different transmission modes? And how do environment and resource availability affect pathogen spread? This project aims to understand the spatio-temporal mechanisms behind rodent-borne disease outbreaks as a response to environmental alterations and resource increase. In addition, this project will provide a framework for assessing the risk of future epidemics, using human population mapping and climate change scenarios, and throw light on zoonoses future transmission.


Diana is an environmental engineer interested in the effects of environmental change in infectious disease dynamics. During her PhD at the University of Los Andes (Colombia, 2018), she studied the impacts of oil palm plantations in the parasite transmission of Chagas disease. Afterwards, she did a one-year post-doc in the Vignuzzi lab at Institut Pasteur (2018-2019) and a second post-doc in the group of Andy Fenton at the University of Liverpool (2019-2021). She joined SpELL in June 2021 to study the spatio-temporal dynamics of rodent borne diseases in Western Europe. Her work will throw light on the future of rodent-borne disease transmission dynamics under future climate conditions and human mobility.


Who acquires infection from whom? Estimating herpesvirus transmission rates between wild rodent host groups
D. Erazo, A. B. Pedersen, K. Gallagher, and A. Fenton. "Epidemics", Vol. 35, Pages 100451, 2021.

Defective viral genomes from chikungunya virus are broad-spectrum antivirals and prevent virus dissemination in mosquitoes
L. I. Levi, V. V. Rezelj, A. Henrion-Lacritick, D. Erazo, J. Boussier, T. Vallet, V. Bernhauerová, Y. Suzuki, L. Carrau, J. Weger-Lucarelli, M.-C. Saleh, and M. Vignuzzi. "PLoS Pathogens", Vol. 17, Issue 2, Pages e1009110, 2021.

Measuring spatial co-occurrences of species potentially involved in Leishmania transmission cycles through a predictive and fieldwork approach
M. López, D. Erazo, J. Hoyos, C. León, P. Fuya, L. Lugo, J. M. Cordovez, and C. González. "Scientific Reports", Vol. 11, Issue 1, Pages 6789, 2021.

Defective viral genomes as therapeutic interfering particles against flavivirus infection in mammalian and mosquito hosts
V. V. Rezelj, L. Carrau, F. Merwaiss, L. I. Levi, D. Erazo, Q. D. Tran, A. Henrion-Lacritick, V. Gausson, Y. Suzuki, D. Shengjuler, B. Meyer, T. Vallet, J. Weger-Lucarelli, V. Bernhauerová, A. Titievsky, V. Sharov, S. Pietropaoli, M. A. Diaz-Salinas, V. Legros, N. Pardigon, G. Barba-Spaeth, L. Brodsky, M.-C. Saleh, and M. Vignuzzi. "Nature Communications", Vol. 12, Issue 1, Pages 2290, 2021.

Rhodnius prolixus Colonization and Trypanosoma cruzi transmission in oil palm (Elaeis guineensis) plantations in the Orinoco Basin, Colombia
D. Erazo, C. González, F. Guhl, J. D. Umaña, J. A. Morales-Betancourt, and J. Cordovez. "The American Journal of Tropical Medicine and Hygiene", Vol. 103, Issue 1, Pages 428-436,2020.

How microclimatic variables and blood meal sources influence Rhodnius prolixus abundance and Trypanosoma cruzi infection in Attalea butyracea and Elaeis guineensis palms?
J. M. Calderón, D. Erazo, T. J. Kieran, N. L. Gottdenker, C. León, J. Cordovez, F. Guhl, T. C. Glenn, and C. González. "Acta Tropica", Vol. 212, Pages 105674, 2020.

Generalist host species drive Trypanosoma cruzi vector infection in oil palm plantations in the Orinoco region, Colombia
D. Erazo, N. L. Gottdenker, C. González, F. Guhl, M. Cuellar, T. J. Kieran, T. C. Glenn, J. D. Umaña, and J. Cordovez. "Parasites and Vectors", Vol. 12, Issue 1, Pages 274, 2019.

Modelling the influence of host community composition in a sylvatic Trypanosoma cruzi system
D. Erazo, J. Cordovez, C. Cabrera, J. E. Calzada, A. Saldaña, and N. L. Gottdenker. "Parasitology", Vol. 144, Issue 14, Pages 1881-1889, 2017.

Modeling the effects of palm-house proximity on the theoretical risk of Chagas disease transmission in a rural locality of the Orinoco basin, Colombia
D. Erazo, and J. Cordovez. "Parasites and Vectors", Vol. 9, Issue 1, Pages 592, 2016.

The role of light in Chagas disease infection risk in Colombia
D. Erazo, and J. Cordovez. "Parasites and Vectors", Vol. 9, Issue 1, Pages 9, 2016.

New scenarios of Trypanosoma cruzi transmission in the Orinoco region of Colombia
L. M. Rendón, F. Guhl, J. M. Cordovez, and D. Erazo. "Memórias do Instituto Oswaldo Cruz", Vol. 110, Pages 283-288, 2015.